BIOL 568 (Winter)

Topics on the Human Genome



Instructor(s):
 
R. Slim (Coordinator)
Mtl. Gen. Hospital
(514) 934-1934x44550
rima.slim@muhc.mcgill.ca
& Staff
 
R. Mackay (Administrator) TBA (514) 398-4198 ross.mackay@mcgill.ca
       
Workload:
 
3 credits (3-0-6)
 
 
Prerequisite(s):
 
BIOL 202, BIOL 300, BIOL 370 or permission of instructor.
 
 
Content:
 

The course will cover genomic, molecular and cellular approaches to characterization of the human genome.

1. Genome technology and Next generation sequencing methods (1.5 hours)
2. Genome wide association studies including recent results (3 hours)
3. Large-scale data visualization and analysis, RNA and exome sequencing (4.5 hours)
4. Gene organization and regulation (6 hours)
5. DNA Methylation (history, introduction, approaches, and associated human diseases) (6 hours)
6. Genetic mosaicism and de novo mutations in human diseases (3 hours)
7. Genetics of cancer ontogeny (4.5 hours)
8. General developmental genetics and use of pluripotent stem cells (3 hours)
9. Ethical, Legal, and Social Aspects of Human Genomics Research (4.5 hours)
       
Readings:
 
Selected journal articles.
 
 
Method:
 
3 hours lectures.
 
 
Evaluation:
 
Mid-term and final exam.      
McGill University values academic integrity. Therefore all students must understand the meaning and consequences of cheating, plagiarism and other academic offences under the Code of Student Conduct and Disciplinary Procedures (see http://www.mcgill.ca/integrity/ for more information).

Last update: March 22, 2017