Dr. Nam-Sung Moon
Associate Professor


Bradley-Gill MR, Kim M, Feingold D, Yergeau C, Houde J, Moon NS (2016). Alternate transcripts of the Drosophila "activator" E2F are necessary for maintenance of cell cycle exit during development. Developmental Biology 411(2):195-206

Bradley-Gill MR, Kim MH, Feingold D, Yergeau C, Moon NS (2016) Activator E2F is
needed for proper cell cycle exit during development. International RB meeting, Columbus, OH, USA, 2016

Ambrus A, Islam A, Holmes K, Moon NS, López-Bigas N, Benevolenskaya E, Frolov M (2013) Loss of dE2F compromises mitochondrial function. Developmental Cell 27(4):438-51.

Collins H, Moon NS (2013) The components of Drosophila histone chaperone dCAF-1 are required for the cell death phenotype associated with rbf1 mutation. G3: Genes | Genomes | Genetics doi:10.1534/g3.113.007419.

Krivy K, Bradley-Gill MR, Moon NS (2013) Capicua regulates proliferation and survival of RB-deficient cells in Drosophila. Biology Open. 2(2):183-190.

Longworth MS, Walker JA, Anderssen E, Moon NS, Gladden A, Heck MM, Ramaswamy S, Dyson NJ (2012) A shared role for RBF1 and dCAP-D3 in the regulation of transcription with consequences for innate immunity. PLoS genetics 8(4):e1002618.

Popova MK, Korenjak M, He W, Dyson NJ, and Moon NS (2011) Rb deficiency during Drosophila eye development deregulates EMC, causing defects in the development of photoreceptors and cone cells. Journal of Cell Science 124(Pt 24):4203-12.

Hsieh TC, Nicolay B, Frolov M, Moon NS (2010) Tuberous Sclerosis Complex 1 regulates dE2F1 expression during development and cooperates with RBF1 to control proliferation and survival. PLoS Genetics 6(8): e1001071 (Feature image for the August 2010 issue)

Nicolay B, Bayarmagnai B, Moon NS, Benevolenskaya E, Frolov M (2010) Combined inactivation of pRB and Hippo pathways induces dedifferentiation in the Drosophila retina. PLoS Genetics 6(4):e1000918.

Morris EJ, Yuan JY, Yang F, Di Stefano L, Herr A, Moon NS, Kwon EJ, Haigis KM, Näär AM and Dyson NJ. (2008) E2F1 represses ß-catenin transcription and is antagonized by both pRB and CDK8. Nature. 455 (7212):552-6.

Moon NS, Di Stefano L, Morris EJ, Patel R, White K, and Dyson NJ (2008) E2F and p53 induce apoptosis independently during Drosophila development but intersect in the context of DNA damage. PLoS Genetics 4(8):e1000153.

Di Stefano L, Ji JY, Moon NS, Herr A, Dyson NJ (2007) Mutation of Drosophila Lsd1 disrupts H3-K4 methylation, resulting in tissue-specific defects during development. Curr Biology 1;17(9):808-12.

Morris EJ, Michaud WA, Ji JY, Moon NS, Rocco JW, Dyson NJ (2006) Functional identification of Api5 as a suppressor of E2F-dependent apoptosis in vivo. PLoS Genetics 17;2(11):e196.

Moon NS, Di Stefano L, and Dyson NJ (2006) A gradient of EGFR signaling determines the sensitivity of rbf1 mutant cells to E2F-dependent apoptosis. Molecular and Cellular Biology 26(20):7601-15.

Moon NS, Frolov MV, Kwon EJ, Di Stefano L, Dimova DK, Morris EJ, Taylor-Harding B, White K, Dyson NJ (2005) Drosophila E2F1 has context-specific pro- and antiapoptotic properties during development. Developmental Cell 9(4):463-75.

Frolov MV*, Moon NS*, and Dyson NJ. (2005) dDP is required for normal cell proliferation. Molecular and Cellular Biology 25(8):3027-39. (*Equal contribution)

Stevaux O, Dimova DK, Ji JY, Moon NS, Frolov MV, Dyson NJ. (2005) Retinoblastoma family 2 is required in vivo for the tissue-specific repression of dE2F2 target genes. Cell Cycle 4(9):1272-80.

Frolov MV, Stevaux O, Moon NS, Dimova D, Kwon EJ, Morris EJ and Dyson NJ. (2003) G1 cyclin dependent kinases are insufficient to reverse dE2F2-mediated repression. Genes and Development 17(6):723-728.


Collins H and Moon NS. (2015) “dCAF1 is required for the cell death sensitivity of rbf1 mutant cells” 51st Annual Drosophila Research Conference, Chicago, Il, USA

Bradley-Gill MR and Moon NS. (2015) “Identification of the specific de2f1 transcript that is required for the formation of imaginal discs” 51st Annual Drosophila Research Conference, Chicago, Il, USA

Collins H and Moon NS. The genetic interaction between rbf1 and Posterior sex combs reveals a role for histone chaperone dCAF-1 in cell survival (2012) Mechanism of Eukaryotic Transcription, Cold Spring Harbor, USA

Krivy K, Bradley-Gill MR, Moon NS. Capicua mutations promote proliferation and survival of Rb deficient cells in Drosophila. (2012) Society for Developmental Biology 71st annual meeting, Montreal, Canada

An eye-antennal imaginal disc
containing TSC2 mutant clones.
(From Hsieh et al (2010)