Dr. Frieder SCHOECK
[visit the Schöck Lab Website]

Frieder Schöck completed undergraduate studies at the University of Erlangen-Nürnberg and at the University of Edinburgh, and graduate studies in the laboratory of Herbert Jäckle at the Max Planck Institute. During his time at Max Planck he worked on the gap-like gene buttonhead and its role in head development of Drosophila. Dr Schöck joined the laboratory of Norbert Perrimon, Harvard Medical Schoool, as a Postdoctoral Fellow.  During his time at Harvard he investigated the cell shape changes and genes mediating germ band shortening, a morphogenetic process in mid-embryogenesis which allows the study of cell motility by live imaging of the embryo. Frieder Schöck joined the Department of Biology, McGill University, as Assistant Professor, as well as the DBRI, in September 2003 and is Associate Professor since 2009.

Research in the Schöck laboratory.

The Schöck lab studies cell-matrix adhesion and the actin cytoskeleton, in particular, how integrin-associated proteins regulate adhesion during muscle attachment and myofibril assembly in the fruit fly Drosophila. We use Drosophila as a model system because of its unique genetics, which allows us to study the relationship and function of genes in tissues, and because of the high homology of basic cellular processes betweenDrosophila and humans. Our research will shed light on the regulation of integrin adhesion and its coordination with the actin cytoskeleton, and will lead to a better understanding of muscle disorders.

Selected Publications

Katzemich A, Long JY, Jani K, Lee BR, and Schöck F (2011). Muscle type-specific expression of Zasp52 isoforms in Drosophila. Gene Expression Patterns 11, 484-490.

Sparrow JC and Schöck F (2009). The initial steps of myofibril assembly: integrins pave the way. Nature Reviews Molecular Cell Biology 10, 293-298.

Lee S, Zhou L, Kim J, Kalbfleisch S and Schöck F (2008). Lasp anchors the Drosophila male stem cell niche and mediates spermatid individualization. Mechanisms of Development 125, 768-776.

Jani K and Schöck F (2007). Zasp is required for the assembly of functional integrin adhesion sites. Journal of Cell Biology 179, 1583-1597.


Abouheif] [Brouhard] [Dankort] [Dent] [Harrison] [Hekimi]
[Larsson] [Lasko] [Moon] [Nilson] [Roy] [Schöck] [Vogel] [Western] [Zetka]
[Zheng]