Fly Genomic DNA preparation

Before using the service, download the user form and email the complete form at cian@mcgill.ca.
For more information, contact us

What do I provide?

Flat bottom 96-well plate(s) with 5 flies/well
AND
at least 20mL/plate of Buffer A (100mM TrisHCl, pH 7.6; 100 mM NaCl; 100 mM EDTA, 0.5% SDS)

How do I submit samples?

Coordinate with Guillaume Lesage (514-398-5414)
or Ming Wang (514-398-2518 or 5669)
or email at cian@mcgill.ca

When do I submit samples?

Any day before 1:30PM

When can I pick up collection plates?

Same day at 4:00PM

What do I get?

Sealed 96-well plate(s) containing 100µL/well of genomic DNA resuspended in TE

What are the expected results?

Yields may vary among strains. In our setup experiments, we obtained 1-2µg DNA, the quality of which was suitable for PCR.

Which method is used?

Alkali lysis procedure followed by isopropanol precipitation.
Adapted from Parks et al, 2004, Nature Genet. 36:288-92

Any quality control?

To reduce variability and ensure quality, we use commercial solutions and buffers. In addition, a control is included for each batch of preparation, ensuring quality control

I don’t have 96 samples… Can I use the service?

Yes. Partial plate can be run at the cost of a full plate
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